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Home / Primary Antibodies / Polyclonal Antibodies

JNK antibody

SKU : BHA10804436

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Mfr.No.	FNab04444
Background	MAPK8(Mitogen-activated protein kinase 8) is also named as JNK1, PRKM8, SAPK1, SAPK1C and belongs to the MAP kinase subfamily. MAPK8 is activated by dual phosphorylation at a Thr-Pro-Tyr motif during response to UV light. MAPK8 functions to phosphorylate c-Jun at N-terminal serine regulatory sites of Ser-63 and Ser-73, mapping within the transactivation domain. Phosphorylation of these sites in response to UV results in transcriptional activation of c-Jun. It has 4 isoforms produced by alternative splicing with the molecular weight of 46 kDa and 48 kDa.
Categories	Primary Antibodies
Clonality	polyclonal
Host	Rabbit
Immunogen	mitogen-activated protein kinase 8
Isotype	IgG
Molecular Weight	46 kDa, 55 kDa
Reactivity	Human, Mouse, Rat
Regulatory	RUO
Synonyms	c Jun N terminal kinase 1, JNK, JNK 46, JNK1, JNK1A2, JNK21B1/2, MAP kinase 8, MAPK 8, MAPK8, PRKM8, SAPK1

Antigen	JNK
Uniprot	P45983
Gene Id	5599
Research Area	Signal Transduction, Metabolism, Cardiovascular, Immunology, Neuroscience

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IHC, IP
Description	ELISA ; WB ; IHC ; IP
Tested Application	WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Manual	FNab04444.pdf

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SKU	Supplier No.	Size	Your price	Quantity
BHA10804436	FNab04444	100ug	$260		Add to Cart

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