ITGB4 Antibody / Integrin beta 4 / CD104

Mfr.No.	R31440
Clonality	Polyclonal
Description	ITGB4, also known as CD104, is a receptor for the laminin proteins. It tends to associate with alpha 6 subunits and is likely to play a pivotal role in the biology of invasive carcinoma. It was found that ITGB4 was upregulated 6-fold by ZKSCAN3 in transfected human colon cancer cells compared with parental cells and ZKSCAN3 has been confirmed as the promoter of ITGB4 in vitro and in vivo. ITGB4 knockdown by short hairpin RNA countered ZKSCAN3-augmented anchorage-independent colony formation in the colon cancer cell lines.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Human partial recombinant protein (AA 28-266) was used as the immunogen for this ITGB4 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	ITGB4
Uniprot	P16144

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the ITGB4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	FACS, IF, IHC-P, WB
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunofluorescence (FFPE): 1-2ug/ml,Flow cytometry: 1-3ug/million cells