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Home / Primary Antibodies / Polyclonal Antibodies

ITCH Antibody / AIF4

SKU : BHA17105637

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NSJ Bioreagents

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Mfr.No.	R32307
Clonality	Polyclonal
Description	ITCH is an ubiquitin-conjugating enzyme. This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Amino acids AMQQFNQRFIYGNQDLFATSQSKEFDPL of human ITCH were used as the immunogen for the ITCH antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	ITCH
Uniprot	Q96J02

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the ITCH antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Western blot: 0.1-0.5ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17105637-1	R32307	100ug	$439		Add to Cart

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