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Home / Primary Antibodies / Polyclonal Antibodies

Il4 receptor Antibody

SKU : BHA17110823

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NSJ Bioreagents

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Mfr.No.	RQ6186
Clonality	Polyclonal
Description	IL4R (INTERLEUKIN 4 RECEPTOR) is a human gene that encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE antibody production in B cells. The IL4R gene is localized to 16p12.1-p11.2 by in situ hybridization and Southern blot analysis of DNA from a panel of mouse-human somatic cell lines. IL4 plays a major role in immunoglobulin E(IgE) production. Its signal is conferred to effector cells through binding to the alpha chain of the IL4 receptor. IL4 interacts with IL4R with high affinity, leading to dimerization with either the common gamma chain,a component of receptors for a number of cytokines, to create a type I receptor, or with IL13RA1 to form a type II receptor.The IL4R gene contains 12 exons and IL4R is a complex of at least 2 components, one of which is a novel affinity converting subunit that is critical for cellular signal transduction. See also IL13RA1 and IL13RA2.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	A rat recombinant partial protein (amino acids I26-E719) was used as the immunogen for the Il4 receptor antibody.
Isotype	IgG
Predicted Reactivity	Rat, Mouse
Reactivity	Rat, Mouse
Recombinant	No

Antigen	Il4r
Uniprot	Q63257

Format	Antigen affinity purified
Purification	Affinity purified
Storage	After reconstitution, the Il4 receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	Direct ELISA, FACS, IHC-P
Dilution	Immunohistochemistry (FFPE): 2-5ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17110823	RQ6186	100ug	$439		Add to Cart

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