Interleukin 2 receptor beta, also called CD122, is a protein that in humans is encoded by the IL2RB gene. The gene represents the beta subunit and is a type I membrane protein. The IL2RB gene contains 10 exons spanning about 24.3 kb and that the gene product is encoded by exons 2-10. IL-2 receptor is present in three forms with respect to binding ability to IL-2: high, intermediate, and low affinity forms. Analysis of mutants of the beta chain of the IL-2 receptor reveals that the granulocyte and monocyte differentiation signals are triggered by different cytoplasmic domains, showing that the signaling pathways responsible for these unique developmental outcomes are separable.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Amino acids 117-135 (RVMAIQDFKPFENLRLMAP-human) of the beta subunit were used as the immunogen for this IL-2 Receptor antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Antigen
IL-2 Receptor
Uniprot
P14784
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the IL-2 Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.