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Home / Primary Antibodies / Polyclonal Antibodies

IkB beta Antibody

SKU : BHA17105074

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NSJ Bioreagents

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Mfr.No.	R31705
Clonality	Polyclonal
Description	NF-kappa-B inhibitor beta, also known as IKBB or TRIP9, is a protein that in humans is encoded by the NFKBIB gene. The protein encoded by this gene belongs to the <a href=../search_result.php?search_txt=nfkb>NF-kappa-B</a> inhibitor family, which inhibit NF-kappa-B by complexing with it and therebye trapping it in the cytoplasm. It has been found that in vivo, IkB beta serves both to inhibit and to facilitate the inflammatory response. Its degradation releases NF-kappa-B dimers, which upregulate proinflammatory target genes such as <a href=../search_result.php?search_txt=tnf alpha>TNF-alpha</a>. Surprisingly, absence of IkB beta results in a dramatic reduction of TNF-alpha in response to lipopolysaccharide, even though activation of NF-kappa-B is normal.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Human partial recombinant protein (AA 56-237) was used as the immunogen for this IkB beta antibody.
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No
Subcellular Location	Cytoplasmic & Nuclear

Antigen	IkB beta
Gene Id	4793

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the IkB beta antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	IHC-P, WB
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17105074	R31705	100ug	$439		Add to Cart

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