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Home / Primary Antibodies / Polyclonal Antibodies

Iduronate 2 sulfatase Antibody

SKU : BHA17104531

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NSJ Bioreagents

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Mfr.No.	R31017
Clonality	Polyclonal
Description	Iduronate 2 sulfatase (IDS) is an enzyme associated with Hunter syndrome. IDS is involved in the lysosomal degradation of the glycosaminoglycans heparan sulfate and dermatan sulfate. Wilson et al.(1991) used an IDS cDNA clone to localize the gene to Xq28, distal to the fragile X site. Faust et al.(1992) and Daniele et al.(1993) demonstrated that the homologous Ids gene in the mouse occupies the same position on the X chromosome in relation to the FMR1, F9, and GABRA3 genes. IDS is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked mucopolysaccharidosis type II, also known as Hunter syndrome. Iduronate 2 sulfatase has a strong sequence homology with human arylsulfatases A, B, and C, and human glucosamine-6sulfatase.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the C-terminus of human IDS (ELCREGKNLLKHFRFRDLE) was used as the immunogen for this Iduronate 2 sulfatase antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	Iduronate 2 sulfatase
Uniprot	P22304

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the Iduronate 2 sulfatase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, IHC-P
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17104531-1	R31017	100ug	$439		Add to Cart

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