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Home / Primary Antibodies / Polyclonal Antibodies

HSD17B2 Antibody

SKU : BHA17104281

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NSJ Bioreagents

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Mfr.No.	R30683
Clonality	Polyclonal
Description	HSD17B2(17-beta-hydroxysteroid dehydrogenase II), also called 17-beta-HSD II, is an enzyme with 387 amino acids, a predicted molecular weight of 42,782D, and associate with the membranes of the endoplasmic reticulum. The type 2 enzyme is capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. HSD17B2 mRNA was detected in 18 of 42 (43%) adenomas but not in prolactinomas. In the human endometrium, inactivation of 17-beta-estradiol to estrone is catalyzed by HSD17B2. And it activity distinguishing between disease-free and diseased endometria. It efficiently catalyzes the oxidative metabolism of androgens and estrogens, and it is expressed in a large series of human peripheral tissues. The previous paradigm that HSD17B2 activity in the endometrium is elevated during the secretory phase is confined to diseased endometrium but not to disease-free endometrium.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Amino acids 373-387 (MPRALRMPNYKKKAT-human) were used as the immunogen for this HSD17B2 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	HSD17B2
Uniprot	P37059

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the HSD17B2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	IHC-F, IHC-P, WB
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunohistochemistry (Frozen): 0.5-1ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17104281-1	R30683	100ug	$439		Add to Cart

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