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Home / Primary Antibodies / Polyclonal Antibodies

HSD11B1 Antibody / 11-beta-hydroxysteroid dehydrogenase type 1

SKU : BHA17104107

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NSJ Bioreagents

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Mfr.No.	R30441
Clonality	Polyclonal
Description	11beta-hydroxysteroid dehydrogenase type 1 is an NADPH-dependent enzyme highly expressed in key metabolic tissues including liver, adipose tissue, and the central nervous system. In these tissues, HSD11B1 reduces cortisone to the active hormone cortisol that activates glucocorticoid receptors. It is inhibited by carbenoxolone, a drug typically used in the treatment of peptic ulcers. Tannin et al.(1991) localized the HSD11B1 gene to chromosome 1. The localization was confirmed by isolating the gene from a chromosome 1-specific library using the cDNA as a probe. Schutte et al.(2000) mapped the HSD11B1 gene to 1q32-q41.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the N-terminus of human HSD11B1 (MAYYYYSANEEFRPEMLQ) was used as the immunogen for this HSD11B1 antibody.
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No

Antigen	HSD11B1
Uniprot	P28845

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the HSD11B1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	IHC-P, WB
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17104107-1	R30441	100ug	$439		Add to Cart

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