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Home / Primary Antibodies / Polyclonal Antibodies

HLA-DM Antibody (beta chain)

SKU : BHA17104425

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NSJ Bioreagents

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Mfr.No.	R30885
Clonality	Polyclonal
Description	Major histocompatibility complex, class II, DM beta, also known as D6S221E, RING7, HLA-DM histocompatibility type, beta chain, HLADMB or RING7, is a protein that in humans is encoded by the HLADMB gene. HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chains, both anchored in the membrane. It is located in intracellular vesicles. The protein plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells. The beta chain is approximately 26-28 kDa and its gene contains 6 exons. HLA-DMA and -DMB appear to encode subunits of a functional heterodimer that is critical in the pathway of class II antigen presentation.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the middle region of human HLA-DM beta chain (NQKDTLMQRLRNGLQNCATH) was used as the immunogen for this HLA-DM antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	HLA-DM
Uniprot	P28068

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the HLA-DM antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, IHC-P
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17104425-1	R30885	100ug	$439		Add to Cart

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