Small GTPase required for proper nuclear import of RNA polymerase II(RNAPII)(PubMed:20855544, PubMed:21768307). May act at an RNAP assembly step prior to nuclear import(PubMed:21768307). Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation(PubMed:17643375). May be involved in nuclear localization of XPA(PubMed:11058119).
Categories
Primary Antibodies
Clonality
polyclonal
Description
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307). May act at an RNAP assembly step prior to nuclear import (PubMed:21768307). Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375). May be involved in nuclear localization of XPA (PubMed:11058119).
Host
Rabbit
Immunogen
GPN-loop GTPase 1
Isotype
IgG
Molecular Weight
41kd
Reactivity
Human
Regulatory
RUO
Synonyms
MBDIN, RPAP4,
Antigen
GPN1
Uniprot
Q9HCN4
Gene Id
11321
Research Area
Metabolism
Form
liquid
Format
liquid
Purification
Immunogen affinity purified
Purity
>=95% as determined by SDS-PAGE
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)