Trans-acting T-cell-specific transcription factor GATA-3, also named HDR, is a protein that in humans is encoded by the GATA3 gene. It is mapped to 10p14. This gene belongs to the GATA family of transcription factors. It regulates luminal epithelial cell differentiation in the mammary gland. The protein contains two GATA-type zinc fingers, it is an important regulator of T cell development and plays an important role in endothelial cell biology. GATA3 has been shown to promote the secretion of<a href=../search_result.php?search_txt=il-4>IL-4</a>,<a href=../search_result.php?search_txt=il-5>IL-5</a>, and<a href=../search_result.php?search_txt=il-13>IL-13</a>from Th2 cells, and induces the differentiation of Th0 cells towards this T cell subtype while suppressing their differentiation towards Th1 cells.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Human partial recombinant protein (AA 1-197) was used as the immunogen for this GATA3 antibody.
Isotype
IgG
Predicted Reactivity
Human, Rat
Reactivity
Rat, Human
Recombinant
No
Antigen
GATA3
Gene Id
2625
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the GATA3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.