Catenin gamma, also known as Junction plakoglobin (JUP) or Plakoglobin (PKGB), is a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. Catenin beta and gamma, vertebrate homologs of Drosophila armadillo, function in cell adhesion and the Wnt signaling pathway. Catenin gamma may have distinct roles in Wnt signaling and cancer via differential effects on downstream target genes.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
An amino acid sequence from the N-terminus of human gamma Catenin (LLATQVEGQATNLQRLAE) was used as the immunogen for this gamma Catenin antibody.
Isotype
IgG
Predicted Reactivity
Human, Mouse, Rat
Reactivity
Human, Mouse, Rat
Recombinant
No
Antigen
Gamma Catenin
Uniprot
P14923
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the gamma Catenin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.