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Home / Primary Antibodies / Polyclonal Antibodies

FRZB Antibody

SKU : BHA17105624

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NSJ Bioreagents

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Mfr.No.	R32294
Clonality	Polyclonal
Description	FRZB is also known as FRE or OS1. The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility. FRZB is a Wnt-binding protein especially important in embryonic development. It is a competitor for the cell-surface G-protein receptor Frizzled. FRZB is localized in the extracellular plasma membrane. Unlike frizzled, frzb lacks the 7 transmembrane domains normally found in G-protein-coupled receptors. It is still considered a homolog of frizzled because it contains a Cysteine Rich Domain (CRD), and because of its intracellular C-terminus which is crucial for signaling.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Amino acids 176-325 of human FRZB were used as the immunogen for the FRZB antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	FRZB
Uniprot	Q92765

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the FRZB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, ELISA
Dilution	Western blot: 0.1-0.5ug/ml,ELISA: 0.1-0.5ug/ml (human protein tested); request BSA-free format for coating

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17105624	R32294	100ug	$439		Add to Cart

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