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Home / Primary Antibodies / Polyclonal Antibodies

FAT10 Antibody / Ubiquitin D / UBD

SKU : BHA17104780

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NSJ Bioreagents

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Mfr.No.	R31346
Clonality	Polyclonal
Description	Ubiquitin D, Diubiquitin or FAT10 (HLA-F-adjacent transcript 10), is a protein that in humans is encoded by the UBD gene. It is a ubiquitin-like protein modifier that can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome in a NUB1L-dependent manner. This gene may be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses. It may be involved in the formation of aggresomes when proteasome is saturated or impaired. FAT10 mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN). It may also function as a survival factor.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An amino acid sequence from the N-terminus of human HLA-F-adjacent transcript 10 (YDSVKKIKEHVRSK) was used as the immunogen for this FAT10 antibody.
Isotype	IgG
Predicted Reactivity	Human
Reactivity	Human
Recombinant	No

Antigen	FAT10
Uniprot	O15205

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the FAT10 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, IHC-P
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17104780-1	R31346	100ug	$439		Add to Cart

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