EH-domain containing 2, also known as EHD2, is a human gene belonging to the EHD protein family. This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Amino acids KKQLILKLPVIFAKIQLEHH from the human protein were used as the immunogen for the EHD2 antibody.
Isotype
Rabbit IgG
Species Reactivity
Human
Note
Optimal dilution of the EHD2 antibody should be determined by the researcher.
Uniprot
Q9NZN4
Format
Antigen affinity purified
Purity
Affinity purified
Storage
After reconstitution, the EHD2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.