Anhidrotic ectodermal dysplasia is an X-linked recessive disorder which affects ectodermal structures. Ectodysplasin-A, the protein encoded by the EDA gene, is a member of the tumor necrosis factor ligand superfamily that forms a collagen triple helix, suggesting functions in signal transduction and cell adhesion. Wnt signaling controls EDA gene expression, but Ectodysplasin-A does not feedback on the Wnt pathway.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
An amino acid sequence from the middle region of human EDA (HLQGQGSAIQVKNDLS) was used as the immunogen for this EDA antibody (100% homologous in human, mouse and rat).
Isotype
IgG
Predicted Reactivity
Human, Mouse, Rat
Reactivity
Human, Mouse, Rat
Recombinant
No
Antigen
EDA
Uniprot
Q92838
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the EDA antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.