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Home / Primary Antibodies / Polyclonal Antibodies

DJ-1 Antibody / PARK7

SKU : BHA17105089

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NSJ Bioreagents

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Mfr.No.	R31721
Clonality	Polyclonal
Description	Parkinson disease 7, also known as Protein deglycase DJ-1, is a protein which in humans is encoded by the PARK7 gene. PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It is also involved in tumorigenesis and in maintaining mitochondrial homeostasis. DJ-1 may function as a redox-sensitive chaperone, as a sensor foroxidative stress, and it apparently protects neurons against oxidative stress and cell death. It has been found that DJ-1 mutations that impair transcriptional coactivator function can render dopaminergic neurons vulnerable to apoptosis and may contribute to the pathogenesis of Parkinson disease.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Human partial recombinant protein (AA 2-189) was used as the immunogen for this DJ-1 antibody.
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No
Subcellular Location	Cytoplasmic & Nuclear

Antigen	DJ-1
Gene Id	11315

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the DJ-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	IHC-P, WB
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17105089-1	R31721	100ug	$439		Add to Cart

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