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Home / Primary Antibodies / Polyclonal Antibodies

Dicer Antibody

SKU : BHA17122808

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NSJ Bioreagents

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Mfr.No.	RQ6547
Clonality	Polyclonal (rabbit origin)
Description	Dicer (DICER1), also known as endoribonuclease Dicer or helicase with RNase motif, is an enzyme that in humans is encoded by the DICER1 gene. It is mapped to 14q32.13. The DICER1 gene, a member of the ribonuclease III (RNase III) family, is involved in the generation of microRNAs (miRNAs), which modulate gene expression at the post-transcriptional level. DICER1 possesses an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus DICER, also known as helicase-MOI, is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. In addition, DICER1 is required for formation of the RNA induced silencing complex (RISC). It also cleaves double-stranded RNA to produce short interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An E. coli-derived human protein (amino acids Y1546-S1922) was used as the immunogen for the Dicer antibody.
Isotype	Rabbit IgG
Species Reactivity	Human, Mouse
Note	Optimal dilution of the Dicer antibody should be determined by the researcher.

Uniprot	Q9UPY3

Format	Antigen affinity purified
Purity	Affinity purified
Storage	After reconstitution, the Dicer antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	WB, IF, FACS, Direct ELISA
Description	Western blot: 1-2ug/ml,Immunofluorescence: 5ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17122808	RQ6547	100ug	$439		Add to Cart

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