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Home / Primary Antibodies / Polyclonal Antibodies

Ddit3 Antibody / Chop / Gadd153

SKU : BHA17122729

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NSJ Bioreagents

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Mfr.No.	RQ6468
Clonality	Polyclonal (rabbit origin)
Description	DNA damage-inducible transcript 3, also known as C/EBP homologous protein (CHOP), is a pro-apoptotic transcription factor that is encoded by the DDIT3 gene. It is mapped to 12q13.3. This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	An E. coli-derived mouse protein (amino acids E17-A168) was used as the immunogen for the Ddit3 antibody.
Isotype	Rabbit IgG
Species Reactivity	Mouse, Rat
Note	Optimal dilution of the Ddit3 antibody should be determined by the researcher.

Uniprot	P35639

Format	Antigen affinity purified
Purity	Affinity purified
Storage	After reconstitution, the Ddit3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	Direct ELISA, FACS, WB
Description	Western blot: 1-2ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml

Product Manual	Datasheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17122729	RQ6468	100ug	$439		Add to Cart

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