Cytochrome P450, Family 2, Subfamily U, Polypeptide 1 is a protein that in humans is encoded by the CYP2U1 gene. Members of the P450 enzyme family have roles in the tissue-specific conversion of substrates into locally active hormones, vitamins, and signaling molecules, including arachidonic acid derivatives known as eicosanoids. The International Radiation Hybrid Mapping Consortium mapped the gene to chromosome 4.Chuang et al.(2004) stated that CYP2U1 maps to 4q25. Using recombination experiments in Sf9 insect cells, Chuang et al.(2004) found that CYP2U1 metabolized arachidonic acid, docosahexaenoic acid(DHA), and other long chain fatty acids. Chuang et al.(2004) suggested that CYP2U1 may play a role in brain and immune functions.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
An amino acid sequence from the C-terminus of human Cytochrome P450, Family 2, Subfamily U, Polypeptide 1 (EKPEDFYPNRFLDDQGQ) was used as the immunogen for this CYP2U1 antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Antigen
CYP2U1
Uniprot
Q7Z449
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the CYP2U1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Applications
ICC, IHC-P, WB
Dilution
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml