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Home / Primary Antibodies / Polyclonal Antibodies

COMT Antibody

SKU : BHA17109358

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Mfr.No.	RQ4554
Clonality	Polyclonal
Description	Catechol O-methyltransferase, also called COMT, is one of the major mammalian enzymes involved in the metabolic degradation of catecholamines. This gene is mapped to 22q11.21. Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Amino acids R20-S265 from the mouse protein were used as the immunogen for the COMT antibody.
Isotype	IgG
Predicted Reactivity	Mouse
Reactivity	Mouse
Recombinant	No

Antigen	COMT
Uniprot	O88587

Format	Purified
Purification	Antigen affinity purified
Storage	After reconstitution, the COMT antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB, Direct ELISA
Dilution	Western blot: 0.5-1ug/ml,Direct ELISA: 0.1-0.5ug/ml (recombinant mouse protein)

Product Manual	Data Sheet

No Description Available.

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SKU	Supplier No.	Size	Your price	Quantity
BHA17109358	RQ4554	100ug	$439		Add to Cart

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