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Home / Primary Antibodies / Polyclonal Antibodies

CDK3 Antibody (CSB-PA005064LA01HU)

BHA10564370
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Contact us to order
Tel
+1 866.986.9598
Email
orders@biohippo.com
Get a Quote
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Antigen CDK3
Uniprot Q00526
Database Links

HGNC:1772

OMIM:123828

KEGG:hsa:1018

STRING:9606.ENSP00000400088

UniGene:Hs.706766
Function Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle; involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner.
Protein Families Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
Research Area Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Cell biology; Signal transduction
Tissue Specificity Expressed in cancer cell lines and glioblastoma tissue.
Form Liquid
Purification >95%, Protein G purified
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Storage Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Description IHC ; ELISA
Tested Application ELISA, IHC; Recommended dilution: IHC:1:500-1:1000
Datasheet
ELISA Protocol
Immunohistochemistry (IHC) Protocol
SKU Supplier No. Size Your price Quantity
BHA10564370 CSB-PA005064LA01HU 50ug $166
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BHA10564370 CSB-PA005064LA01HU 100ug $299
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