Cluster of Differentiation 82, also called KAI1, is a protein that in humans encoded by the CD82 gene. The gene is mapped to 11p11.2. This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression has been shown to be downregulated in tumor progression of human cancers and can be activated by <a href=../search_result.php?search_txt=p53>p53</a> through a consensus binding sequence in the promoter. The expression of CD82 appears to be correlated with lymph node metastasis in esophageal squamous cell carcinoma (ESCC). And overexpression can suppress tumor invasiveness and metastatic potential by inducing <a href=../search_result.php?search_txt=mmp9>MMP9</a> inactivation via upregulation of <a href=../search_result.php?search_txt=timp1>TIMP1</a>.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Human partial recombinant protein (AA 98-267) was used as the immunogen for this CD82 antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Antigen
CD82
Gene Id
3732
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the CD82 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Applications
WB, IHC-P
Dilution
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml