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Home / Primary Antibodies / Polyclonal Antibodies

Cd2ap antibody

SKU : BHA10801450

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Mfr.No.	FNab01455
Background	Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.
Categories	Primary Antibodies
Clonality	polyclonal
Description	Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T- cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.
Host	Rabbit
Immunogen	CD2-associated protein
Isotype	IgG
Molecular Weight	70 kDa
Reactivity	Human, Mouse
Regulatory	RUO

Antigen	CD2AP
Uniprot	Q9Y5K6
Gene Id	23607
Research Area	Signal Transduction

Form	liquid
Format	liquid
Purification	Immunogen affinity purified
Purity	>=95% as determined by SDS-PAGE
Storage	PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

Applications	ELISA, WB, IF, IP
Description	ELISA ; WB ; IF ; IP
Tested Application	WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100

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SKU	Supplier No.	Size	Your price	Quantity
BHA10801450	FNab01455	100ug	$260		Add to Cart

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