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Home / Primary Antibodies / Polyclonal Antibodies

CD14 Antibody

SKU : BHA17119249

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NSJ Bioreagents

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Mfr.No.	RQ6836
Cellular Localization	secreted, Cytoplasmic
Clonality	Polyclonal (rabbit origin)
Description	CD14 is a single-copy gene encoding 2 protein forms: a 50- to 55-kD glycosylphosphatidylinositol-anchored membrane protein (mCD14) and a monocyte or liver-derived soluble serum protein (sCD14) that lacks the anchor. This gene is located at bands 5q23-q31. The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection of bacterial lipopolysaccharide (LPS). CD14 can bind LPS only in the presence of lipopolysaccharide-binding protein (LBP). Although LPS is considered its main ligand, CD14 also recognizes other pathogen-associated molecular patterns.
Host	Rabbit
Immunogen Region	Recombinant human protein (amino acids T20-N259) was used as the immunogen for the CD14 antibody.
Isotype	Rabbit IgG
Reactivity	Human
Recombinant	No

Antigen	CD14
Uniprot	P08571

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the CD14 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	Direct ELISA, FACS, IF, IHC-P
Dilution	Immunohistochemistry (FFPE): 2-5ug/ml,Immunofluorescence (FFPE): 5ug/ml,Flow cytometry: 1-3ug/million cells,Direct ELISA: 0.1-0.5ug/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119249	RQ6836	100ug	$439		Add to Cart

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