C-C chemokine receptor type 9, also called GPR-9-6 or CDw199, is a protein that in humans is encoded by the CCR9 gene. The protein encoded by this gene is a member of the beta chemoking receptor family. By radiation hybrid analysis and organization of BAC contigs by FISH on combed genomic DNA, the gene within the CCR cluster was localized at 3p21.3. It is the receptor for chemokine SCYA25/TECK. This gene subsequently transduces a signal by increasing the intracellular calcium ions level. It is an alternative coreceptor with CD4 for HIV-1 infection. CCR9 may play a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
An amino acid sequence from the N-terminus of human CCR9 (MTPTDFTSPIPNMADDY) was used as the immunogen for this CCR9 antibody.
Isotype
IgG
Predicted Reactivity
Human
Reactivity
Human
Recombinant
No
Antigen
CCR9
Uniprot
P51686
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the CCR9 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.