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Home / Primary Antibodies / Polyclonal Antibodies

CBS Antibody / Cystathionine Beta Synthase

SKU : BHA17103933

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Mfr.No.	R30143
Clonality	Polyclonal
Description	Cystathionine-beta-synthase is an enzyme that in humans is encoded by the CBS gene. It is mapped to 21q22.3 and contains 23 exons, ranging in size from 42 to 299 bp. CBS catalyzes the first step of the transsulfuration pathway, from homocysteine to cystathionine. It uses the cofactor pyridoxal-phosphate (PLP) and can be allosterically regulated by effectors such as the ubiquitous cofactor S-adenosyl-L-methionine (adoMet). This enzyme belongs to the family of lyases, to be specific, the hydro-lyases, which cleave carbon-oxygen bonds. It is a multidomain enzyme composed of an N-terminal enzymatic domain and two CBS domains. The gene is the most common locus for mutations associated with homocystinuria.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Human partial recombinant protein (AA 331-551) was used as the immunogen for this CBS antibody.
Isotype	IgG
Predicted Reactivity	Human, Rat
Reactivity	Human, Rat
Recombinant	No

Antigen	CBS
Gene Id	875

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the CBS antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	IHC-P, WB
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17103933-1	R30143	100ug	$439		Add to Cart

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