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Home / Primary Antibodies / Polyclonal Antibodies

Cathepsin L Antibody / Ctsl

SKU : BHA17119270

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NSJ Bioreagents

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Mfr.No.	RQ6858
Clonality	Polyclonal (rabbit origin)
Description	The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Additionally, this protein cleaves the S1 subunit of the SARS-CoV-2 spike protein, which is necessary for entry of the virus into the cell.
Host	Rabbit
Immunogen Region	Amino acids KYRAEFAVANDTGFVDIPQQ from the mouse protein were used as the immunogen for the Cathepsin L antibody.
Isotype	Rabbit IgG
Reactivity	Rat, Mouse
Recombinant	No

Antigen	Cathepsin L
Uniprot	P06797

Buffer	Lyophilized from 1X PBS with 2% Trehalose
Concentration	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Format	Antigen affinity purified
Purification	Antigen affinity purified
Storage	After reconstitution, the Cathepsin L antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Applications	FACS, IHC-P, WB
Dilution	Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 2-5ug/ml,Flow cytometry: 1-3ug/million cells

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SKU	Supplier No.	Size	Your price	Quantity
BHA17119270	RQ6858	100ug	$439		Add to Cart

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