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Home / Primary Antibodies / Polyclonal Antibodies

Calcium Sensing Receptor Antibody / CASR

SKU : BHA17105735

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NSJ Bioreagents

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Mfr.No.	R32416
Clonality	Polyclonal
Description	The calcium-sensing receptor (CaSR) is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Amino acids Q926-S1078 of the human protein were used as the immunogen for the Calcium Sensing Receptor antibody.
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No
Subcellular Location	Cytoplasmic, membranous

Antigen	Calcium Sensing Receptor
Uniprot	P41180

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the Calcium Sensing Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	IHC-P, WB
Dilution	Western blot: 0.1-0.5ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17105735-1	R32416	100ug	$439		Add to Cart

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