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Home / Primary Antibodies / Polyclonal Antibodies

Bub1 Antibody

SKU : BHA17104942

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NSJ Bioreagents

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Mfr.No.	R31556
Clonality	Polyclonal
Description	Budding uninhibited by benzimidazoles 1, also known as Mitotic checkpoint serine/threonine kinase, is an enzyme that in humans is encoded by the BUB1 gene. It was first identified in genetic screens of Saccharomyces cerevisiae. The protein is bound to kinetochores and plays a key role in the establishment of the mitotic spindle checkpoint and chromosome congression. The mitotic checkpoint kinase is evolutionary conserved in organisms as diverse as Saccharomyces cerevisiae and humans. Loss-of-function mutations or absence of Bub1 has been reported to result in aneuploidy, chromosomal instability (CIN) and premature senescence. Bub1 possesses versatile and distinct functions during the cell cycle, mainly in the SAC and chromosome alignment during metaphase.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Human partial recombinant protein (AA 731-1085) was used as the immunogen for this Bub1 antibody.
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Human, Mouse, Rat
Recombinant	No

Antigen	Bub1
Gene Id	699

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the Bub1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	WB
Dilution	Western blot: 0.5-1ug/ml

Product Manual	Data Sheet

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA17104942-1	R31556	100ug	$439		Add to Cart

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