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Home / Primary Antibodies / Polyclonal Antibodies

Beclin 1 Antibody

SKU : BHA17104898

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NSJ Bioreagents

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Mfr.No.	R31504
Clonality	Polyclonal
Description	Beclin 1, also known as also known as ATG6 or VPS30 is a protein that in humans is encoded by the BECN1 gene. Beclin 1 and its binding partner class III phosphoinositide 3-kinase (PI3K), also named Vps34, are required for the initiation of the formation of the autophagosome in autophagy. This gene participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration. Schizophrenia is associated with low levels of the protein in the hippocampus of the affected which causes diminished autophagy which in turn results in increased neuronal cell death. It has been found that Beclin 1 can promote autophagy in autophagy-defective yeast with a targeted disruption of apg6/vps30, and in human MCF7 breast carcinoma cells.
Formulation	0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host	Rabbit
Immunogen Region	Human partial recombinant protein (AA 1-354) was used as the immunogen for this Beclin 1 antibody.
Isotype	IgG
Predicted Reactivity	Human, Mouse, Rat
Reactivity	Rat, Human, Mouse
Recombinant	No

Antigen	Beclin 1
Gene Id	8678

Format	Antigen affinity purified
Purification	Antigen affinity
Storage	After reconstitution, the Beclin 1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Applications	IHC-P, WB, FACS
Dilution	Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells

Product Manual	Data Sheet

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SKU	Supplier No.	Size	Your price	Quantity
BHA17104898	R31504	100ug	$439		Add to Cart

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