AP2 alpha, or BOFS, is a protein that in humans is encoded by the TFAP2A gene. It is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. TFAP2A acts as a sequence-specific DNA-binding transcription factor recognizing and binding to the specific DNA sequence and recruiting transcription machinery. This gene is expressed in neural crest cell lineages with the highest levels of expression corresponding to early neural crest cells, suggesting that TFAP2A plays a role in their differentiation and development.
Formulation
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Host
Rabbit
Immunogen Region
Human partial recombinant protein (AA 1-166) was used as the immunogen for this AP2 alpha antibody.
Isotype
IgG
Predicted Reactivity
Human, Rat
Reactivity
Rat, Human
Recombinant
No
Antigen
AP2 alpha
Gene Id
7020
Format
Antigen affinity purified
Purification
Antigen affinity
Storage
After reconstitution, the AP2 alpha antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.