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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Wnt5a Antibody Picoband®

SKU : BHA21007519

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Mfr.No.	PB9063, PB9063-10ug, PB9063-Biotin, PB9063-Cy3, PB9063-Dylight488, PB9063-Dylight550, PB9063-Dylight594, PB9063-FITC, PB9063-HRP, PB9063-APC, PB9063-PE, PB9063-iFluor647, PB9063-carrier-free
Alternative Names	Protein Wnt-5a
Background	Protein Wnt-5a is a protein that in humans is encoded by the WNT5A gene. This gene is a member of the WNT gene family. The WNTs comprise a large class of secreted proteins that control essential developmental processes such as embryonic patteing, cell growth, migration, and differentiation. It is mapped to 3p14.3. WNT5A is highly expressed in the dermal papilla of depilated skin. This protein plays an essential role in regulating developmental pathways during embryogenesis. And this protein may also play a role in oncogenesis. WNT5A and DVL can promote axon differentiation mediated by the PAR3-PAR6-aPKC complex.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Wnt5a Antibody Picoband® catalog # PB9063. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the ca
Host	Rabbit
Immunogen Region	E.coli-derived human Wnt5a recombinant protein (Position: D184-D303). Human Wnt5a shares 100% amino acid (aa) sequence identity with both mouse and rat Wnt5a.
Isotype	Rabbit IgG
Molecular Weight	45 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Protein Wnt-5a;WNT5A;
Tissue Specificity	Expression is increased in differentiated thyroid carcinomas compared to normal thyroid tissue and anaplastic thyroid tumors where expression is low or undetectable. Expression is found in thyrocytes but not in stromal cells (at protein level). .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P41221
Gene Id	7474
Gene Name	WNT5A
Sequence	Belongs to the Wnt family.
Subcellular Location	Secreted, extracellular space, extracellular matrix.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat Weste blot, 0.1-0.5ug/ml, Human, Rat, Mouse

Reference	1. "Entrez Gene: WNT5A wingless-type MMTV integration site family, member 5A" 2. Mikels, A. J., Nusse, R. Purified Wnt-5a protein activates or inhibits beta-catenin-TCF signaling depending on receptor context. PLoS Biol. 4: e115, 2006. 3. Zhang, X., Zhu, J., Yang, G.-Y., Wang, Q.-J., Qian, L., Chen, Y.-M., Chen, F., Tao, Y., Hu, H.-S., Wang, T., Luo, Z.-G. Dishevelled promotes axon differentiation by regulating atypical protein kinase C. Nature Cell Biol. 9: 743-754, 2007.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007519-1	PB9063	-	100 ug	$370		Add to Cart
BHA21007519-2	PB9063-10ug	Sample	10 ug	$99		Add to Cart
BHA21007519-3	PB9063-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007519-4	PB9063-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007519-5	PB9063-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007519-6	PB9063-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007519-7	PB9063-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007519-8	PB9063-FITC	FITC	100 ug	$570		Add to Cart
BHA21007519-9	PB9063-HRP	HRP	100 ug	$570		Add to Cart
BHA21007519-10	PB9063-APC	APC	100 ug	$670		Add to Cart
BHA21007519-11	PB9063-PE	PE	100 ug	$670		Add to Cart
BHA21007519-12	PB9063-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007519-13	PB9063-carrier-free	carrier-free	100 ug	$370		Add to Cart

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