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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Wnt3 Antibody Picoband®

SKU : BHA21000515

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Mfr.No.	PB9619, PB9619-10ug, PB9619-Biotin, PB9619-Cy3, PB9619-Dylight488, PB9619-Dylight550, PB9619-Dylight594, PB9619-FITC, PB9619-HRP, PB9619-APC, PB9619-PE, PB9619-iFluor647, PB9619-carrier-free
Alternative Names	Proto-oncogene Wnt-3
Background	The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patteing during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98% amino acid identity to mouse Wnt3 protein, and 84% to human WNT3A protein, another WNT gene product. The mouse studies show the requirement of Wnt3 in primary axis formation in the mouse. Studies of the gene expression suggest that this gene may play a key role in some cases of human breast, rectal, lung, and gastric cancer through activation of the WNT-beta-catenin-TCF signaling pathway. This gene is clustered with WNT15, another family member, in the chromosome 17q21 region.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Wnt3 Antibody Picoband® catalog # PB9619. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube (By similarity). .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human Wnt3, identical to the related mouse sequence.
Isotype	Rabbit IgG
Molecular Weight	45 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Proto-oncogene Wnt-3;Proto-oncogene Int-4 homolog;WNT3;INT4;
Tissue Specificity	Testis, brain, and heart.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P56703
Gene Id	7473
Gene Name	WNT3
Sequence	Contains 1 HMG box DNA-binding domain.
Subcellular Location	Secreted, extracellular space, extracellular matrix.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human

Reference	1. "Entrez Gene: WNT3 wingless-type MMTV integration site family, member 3". 2. Liu P, Wakamiya M, Shea MJ et al. (1999). "Requirement for Wnt3 in vertebrate axis formation".Nat. Genet. 22 (4): 3615. 3. Roelink H, Wang J, Black DM, Solomon E, Nusse R (Dec 1993). "Molecular cloning and chromosomal localization to 17q21 of the human WNT3 gene". Genomics 17 (3): 7902.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000515-1	PB9619	100 ug	-	$370		Add to Cart
BHA21000515-2	PB9619-10ug	10 ug	Sample	$99		Add to Cart
BHA21000515-3	PB9619-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000515-4	PB9619-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000515-5	PB9619-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000515-6	PB9619-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000515-7	PB9619-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000515-8	PB9619-FITC	100 ug	FITC	$570		Add to Cart
BHA21000515-9	PB9619-HRP	100 ug	HRP	$570		Add to Cart
BHA21000515-10	PB9619-APC	100 ug	APC	$670		Add to Cart
BHA21000515-11	PB9619-PE	100 ug	PE	$670		Add to Cart
BHA21000515-12	PB9619-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000515-13	PB9619-carrier-free	100 ug	carrier-free	$370		Add to Cart

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