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Home / Primary Antibodies / Polyclonal Antibodies

Anti-VIP Receptor 1/VIPR1 Antibody Picoband®

SKU : BHA21007031

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Mfr.No.	PA1756, PA1756-10ug, PA1756-Biotin, PA1756-Cy3, PA1756-Dylight488, PA1756-Dylight550, PA1756-Dylight594, PA1756-FITC, PA1756-HRP, PA1756-APC, PA1756-PE, PA1756-iFluor647, PA1756-carrier-free
Alternative Names	Vasoactive intestinal polypeptide receptor 1
Background	VIPR1 (Vasoactive intestinal polypeptide receptor 1), also known as VIPR,HVR1, is a protein that in humans is encoded by the VIPR1 gene. Distinct subsets of neural, respiratory, gastrointestinal, and immune cells bear specific high-affinity G protein-coupled receptors for VIP, such as VIPR1. The VIPR1 gene is mapped on 3p22.1. The VIPR1 gene was found to span approximately 22 kb and to be comprised of 13 exons (ranging from 42 to 1,400 bp) and 12 introns (ranging from 0.3 to 6.1 kb). One encodes a VIP receptor consisting of 460 amino acids and having 7 putative transmembrane domains, as do other G protein-coupled receptors. Patients with idiopathic achalasia show a significant difference in the distribution of SNPs affecting VIPR1.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-VIP Receptor 1/VIPR1 Antibody catalog # PA1756. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38. .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human VIP Receptor 1, identical to the related rat and mouse sequences.
Isotype	Rabbit IgG
Molecular Weight	52 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Vasoactive intestinal polypeptide receptor 1;VIP-R-1;Pituitary adenylate cyclase-activating polypeptide type II receptor;PACAP type II receptor;PACAP-R-2;PACAP-R2;VPAC1;VIPR1;
Tissue Specificity	In lung, HT-29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and SUP-T1, but not in the T- cell lines Peer, MOLT-4, HSB and YT. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P32241
Gene Name	VIPR1
Subcellular Location	Cell membrane; Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br>

Reference	1. Couvineau, A., Rouyer-Fessard, C., Darmoul, D., Maoret, J.-J., Carrero, I., Ogier-Denis, E., Laburthe, M. Human intestinal VIP receptor: cloning and functional expression of two cDNA encoding proteins with different N-terminal domains. Biochem. Biophys. Res. Commun. 200: 769-776, 1994.<br /><br />2. Sreedharan, S. P., Huang, J.-X., Cheung, M.-C., Goetzl, E. J. Structure, expression, and chromosomal localization of the type I human vasoactive intestinal peptide receptor gene. Proc. Nat. Acad. Sci. 92: 2939-2943, 1995.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007031-1	PA1756	-	100 ug	$370		Add to Cart
BHA21007031-2	PA1756-10ug	Sample	10 ug	$99		Add to Cart
BHA21007031-3	PA1756-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007031-4	PA1756-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007031-5	PA1756-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007031-6	PA1756-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007031-7	PA1756-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007031-8	PA1756-FITC	FITC	100 ug	$570		Add to Cart
BHA21007031-9	PA1756-HRP	HRP	100 ug	$570		Add to Cart
BHA21007031-10	PA1756-APC	APC	100 ug	$670		Add to Cart
BHA21007031-11	PA1756-PE	PE	100 ug	$670		Add to Cart
BHA21007031-12	PA1756-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007031-13	PA1756-carrier-free	carrier-free	100 ug	$370		Add to Cart

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