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Home / Primary Antibodies / Polyclonal Antibodies

Anti-VEGF/Vegfa Antibody Picoband®

SKU : BHA21001125

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Mfr.No.	A00045, A00045-10ug, A00045-Biotin, A00045-Cy3, A00045-Dylight488, A00045-Dylight550, A00045-Dylight594, A00045-FITC, A00045-HRP, A00045-APC, A00045-PE, A00045-iFluor647, A00045-carrier-free
Alternative Names	Vascular endothelial growth factor A
Background	VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothelial cells. It may be a major regulator of tumor angiogenesis in vivo. It is, however, structurally related to platelet-derived growth factor. VEGF shares homology with the PDGF A chain and B chain, including conservation of all 8 cysteines found in PDGFA and PDGFB. VEGF gene contains 8 exons. And VEGF induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. This gene can also regulate haematopoietic stem cell survival by an inteal autocrine loop mechanism. What s more, it also stimulates neurogenesis in vitro and in vivo.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-VEGF/Vegfa Antibody Picoband® catalog # A00045. Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 re
Host	Rabbit
Immunogen Region	E.coli-derived mouse VEGF recombinant protein (Position: A27-R214). Mouse VEGF shares 89.4% and 98.4% amino acid (aa) sequence identity with human and rat VEGF, respectively.
Isotype	Rabbit IgG
Molecular Weight	27 kDa.
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Vascular endothelial growth factor A;VEGF-A;Vascular permeability factor;VPF;Vegfa;Vegf;
Tissue Specificity	In developing embryos, expressed mainly in the choroid plexus, paraventricular neuroepithelium, placenta and kidney glomeruli. Also found in bronchial epithelium, adrenal gland and in seminiferous tubules of testis. High expression of VEGF continues in kidney glomeruli and choroid plexus in adults.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q00731
Gene Id	22339
Gene Name	Vegfa
Subcellular Location	Isoform VEGF-1: Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Rat, Mouse<br>

Reference	1. Lee, C. G.; Link, H.; Baluk, P.; Homer, R. J.; Chapoval, S.; Bhandari, V.; Kang, M. J.; Cohn, L.; Kim, Y. K.; McDonald, D. M.; Elias, J. A. : Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. Nature Med. 10: 1095-1103, 2004. <br /><br />2. Gerber, H.-P.; Malik, A. K.; Solar, G. P.; Sherman, D.; Liang, X. H.; Meng, G.; Hong, K.; Marsters, J. C.; Ferrara, N. : VEGF regulates haematopoietic stem cell survival by an inteal autocrine loop mechanism. Nature 417: 954-958, 2002. <br /><br />3. Jin, K.; Zhu, Y.; Sun, Y.; Mao, X. O.; Xie, L.; Greenberg, D. A. : Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo. Proc. Nat. Acad. Sci. 99: 11946-11950, 2002.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001125-1	A00045	100 ug	-	$370		Add to Cart
BHA21001125-2	A00045-10ug	10 ug	Sample	$99		Add to Cart
BHA21001125-3	A00045-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001125-4	A00045-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001125-5	A00045-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001125-6	A00045-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001125-7	A00045-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001125-8	A00045-FITC	100 ug	FITC	$570		Add to Cart
BHA21001125-9	A00045-HRP	100 ug	HRP	$570		Add to Cart
BHA21001125-10	A00045-APC	100 ug	APC	$670		Add to Cart
BHA21001125-11	A00045-PE	100 ug	PE	$670		Add to Cart
BHA21001125-12	A00045-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001125-13	A00045-carrier-free	100 ug	carrier-free	$370		Add to Cart

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