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Home / Primary Antibodies / Polyclonal Antibodies

Anti-VEGF/VEGFA Antibody Picoband®

SKU : BHA21006659

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Mfr.No.	PA1080, PA1080-10ug, PA1080-Biotin, PA1080-Cy3, PA1080-Dylight488, PA1080-Dylight550, PA1080-Dylight594, PA1080-FITC, PA1080-HRP, PA1080-APC, PA1080-PE, PA1080-iFluor647, PA1080-carrier-free
Alternative Names	Vascular endothelial growth factor A
Background	VEGF, a homodimeric glycoprotein of relative molecular mass 45,000, is the only mitogen that specifically acts on endothelial cells. It may be a major regulator of tumor angiogenesis in vivo. Vascular endothelial growth factor is a mitogen primarily for vascular endothelial cells. It is, however, structurally related to platelet-derived growth factor. VEGF shares homology with the PDGF A chain and B chain, including conservation of all 8 cysteines found in PDGFA and PDGFB. VEGF gene contains 8 exons. Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. VEGF regulates haematopoietic stem cell survival by an inteal autocrine loop mechanism. Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio <a href="https://www.bosterbio.com/anti-vegf-antibody-a00045-boster.html" style="color:#EA8D28">Anti-VEGF</a>/VEGFA Antibody catalog # PA1080. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 re
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human VEGF, identical to the related mouse and rat sequences.
Isotype	Rabbit IgG
Molecular Weight	27 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Vascular endothelial growth factor A;VEGF-A;Vascular permeability factor;VPF;VEGFA;VEGF;
Tissue Specificity	Isoform VEGF189, isoform VEGF165 and isoform VEGF121 are widely expressed. Isoform VEGF206 and isoform VEGF145 are not widely expressed. A higher level expression seen in pituitary tumors as compared to the pituitary gland. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Uniprot	P15692
Gene Name	VEGFA
Sequence	Belongs to the PDGF/VEGF growth factor family.
Subcellular Location	Secreted . VEGF121 is acidic and freely secreted. VEGF165 is more basic, has heparin-binding properties and, although a signicant proportion remains cell-associated, most is freely secreted. VEGF189 is very basic, it is cell-associated after secretion and is bound avidly by heparin and the extracellular matrix, although it may be released as a soluble form by heparin, heparinase or plasmin.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, By Heat<br>

Reference	1. Lee, C. G.; Link, H.; Baluk, P.; Homer, R. J.; Chapoval, S.; Bhandari, V.; Kang, M. J.; Cohn, L.; Kim, Y. K.; McDonald, D. M.; Elias, J. A. : Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. Nature Med. 10: 1095-1103, 2004. <br /><br />2. Gerber, H.-P.; Malik, A. K.; Solar, G. P.; Sherman, D.; Liang, X. H.; Meng, G.; Hong, K.; Marsters, J. C.; Ferrara, N. : VEGF regulates haematopoietic stem cell survival by an inteal autocrine loop mechanism. Nature 417: 954-958, 2002. <br /><br />3. Jin, K.; Zhu, Y.; Sun, Y.; Mao, X. O.; Xie, L.; Greenberg, D. A. : Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo. Proc. Nat. Acad. Sci. 99: 11946-11950, 2002.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006659-1	PA1080	-	100 ug	$370		Add to Cart
BHA21006659-2	PA1080-10ug	Sample	10 ug	$99		Add to Cart
BHA21006659-3	PA1080-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006659-4	PA1080-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006659-5	PA1080-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006659-6	PA1080-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006659-7	PA1080-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006659-8	PA1080-FITC	FITC	100 ug	$570		Add to Cart
BHA21006659-9	PA1080-HRP	HRP	100 ug	$570		Add to Cart
BHA21006659-10	PA1080-APC	APC	100 ug	$670		Add to Cart
BHA21006659-11	PA1080-PE	PE	100 ug	$670		Add to Cart
BHA21006659-12	PA1080-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006659-13	PA1080-carrier-free	carrier-free	100 ug	$370		Add to Cart

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