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Home / Primary Antibodies / Polyclonal Antibodies

Anti-TRIB2 Antibody Picoband®

SKU : BHA21000801

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Mfr.No.	PB9900, PB9900-10ug, PB9900-Biotin, PB9900-Cy3, PB9900-Dylight488, PB9900-Dylight550, PB9900-Dylight594, PB9900-FITC, PB9900-HRP, PB9900-APC, PB9900-PE, PB9900-iFluor647, PB9900-carrier-free
Alternative Names	Tribbles homolog 2
Background	Tribbles homolog 2 is a protein that in humans is encoded by the TRIB2 gene. This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBP alpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alteatively spliced transcript variants have been found for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-TRIB2 Antibody Picoband® catalog # PB9900. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Interacts with MAPK kinases and regulates activation of MAP kinases. Does not display kinase activity (By similarity). .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human TRIB2, identical to the related mouse sequence.
Isotype	Rabbit IgG
Molecular Weight	39 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Tribbles homolog 2;TRB-2;TRIB2 ;TRB2 ;
Tissue Specificity	Highly expressed in peripheral blood leukocytes. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q92519
Gene Id	28951
Gene Name	TRIB2
Subcellular Location	Cytoplasm . Cytoplasm, cytoskeleton . May associate with the cytoskeleton. .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat Weste blot, 0.1-0.5ug/ml, Human

Reference	1. "Entrez Gene: TRIB2 tribbles homolog 2 (Drosophila)". 2. Hegedus Z, Czibula A, Kiss-Toth E (Aug 2006). "Tribbles: novel regulators of cell function; evolutionary aspects". Cell Mol Life Sci 63 (14): 163241. 3. Keeshan K, He Y, Wouters BJ, Shestova O, Xu L, Sai H, Rodriguez CG, Maillard I, Tobias JW, Valk P, Carroll M, Aster JC, Delwel R, Pear WS (Nov 2006). "Tribbles homolog 2 inactivates C/EBPalpha and causes acute myelogenous leukemia". Cancer Cell 10 (5): 40111.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000801-1	PB9900	100 ug	-	$370		Add to Cart
BHA21000801-2	PB9900-10ug	10 ug	Sample	$99		Add to Cart
BHA21000801-3	PB9900-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000801-4	PB9900-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000801-5	PB9900-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000801-6	PB9900-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000801-7	PB9900-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000801-8	PB9900-FITC	100 ug	FITC	$570		Add to Cart
BHA21000801-9	PB9900-HRP	100 ug	HRP	$570		Add to Cart
BHA21000801-10	PB9900-APC	100 ug	APC	$670		Add to Cart
BHA21000801-11	PB9900-PE	100 ug	PE	$670		Add to Cart
BHA21000801-12	PB9900-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000801-13	PB9900-carrier-free	100 ug	carrier-free	$370		Add to Cart

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