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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Triadin/TRDN Antibody Picoband®

SKU : BHA21004647

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Mfr.No.	A06901, A06901-10ug, A06901-Biotin, A06901-Cy3, A06901-Dylight488, A06901-Dylight550, A06901-Dylight594, A06901-FITC, A06901-HRP, A06901-APC, A06901-PE, A06901-iFluor647, A06901-carrier-free
Alternative Names	ADAM metallopeptidase domain 28
Background	This gene encodes an integral membrane protein found in skeletal and cardiac muscle. The encoded protein plays a role in skeletal muscle excitation-contraction coupling as part of the calcium release complex and is required for normal skeletal muscle strength. This protein inly links triads and microtubules in skeletal muscle. Mutations in this gene are associated with cardiac arrythmia syndrome and some variants in this gene may be associated with sudden cardiac death.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Triadin/TRDN Antibody Picoband® catalog # A06901. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	May play a role in the adhesive and proteolytic events that occur during lymphocyte emigration or may function in ectodomain shedding of lymphocyte surface target proteins, such as FASL and CD40L. May be involved in sperm maturation.
Host	Rabbit
Immunogen Region	E.coli-derived human Triadin/TRDN recombinant protein (Position: M67-Q729).
Isotype	Rabbit IgG
Molecular Weight	25 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Disintegrin and metalloproteinase domain-containing protein 28;ADAM 28;3.4.24.-;Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II;eMDC II;Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L;MDC-L;ADAM28;ADAM23, MDCL;
Tissue Specificity	Expressed predominantly in secondary lymphoid tissues, such as lymph node, spleen, small intestine, stomach, colon, appendix and trachea. The lymphocyte population is responsible for expression of this protein in these tissues. Isoform 2 is expressed preferentially in spleen.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q13061
Gene Id	10345
Gene Name	TRDN
Subcellular Location	Isoform 1: Cell membrane; Single-pass type I membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Altmann, H. M., Tester, D. J., Will, M. L., Middha, S., Evans, J. M., Eckloff, B. W., Ackerman, M. J. Homozygous/compound heterozygous triadin mutations associated with autosomal-recessive long-QT syndrome and pediatric sudden cardiac arrest: elucidation of the triadin knockout syndrome. Circulation 131: 2051-2060, 2015. 2. Chopra, N., Yang, T., Asghari, P., Moore, E. D., Huke, S., Akin, B., Cattolica, R. A., Perez, C. F., Hlaing, T., Knollmann-Ritschel, B. E. C., Jones, L. R., Pessah, I. N., Allen, P. D., Franzini-Armstrong, C., Knollmann, B. C. Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias. Proc. Nat. Acad. Sci. 106: 7636-7641, 2009. 3. Hong, C.-S., Ji, J.-H., Kim, J. P., Jung, D. H., Kim, D. H. Molecular cloning and characterization of mouse cardiac triadin isoforms. Gene 278: 193-199, 2001.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004647-1	A06901	-	100 ug	$370		Add to Cart
BHA21004647-2	A06901-10ug	Sample	10 ug	$99		Add to Cart
BHA21004647-3	A06901-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004647-4	A06901-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004647-5	A06901-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004647-6	A06901-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004647-7	A06901-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004647-8	A06901-FITC	FITC	100 ug	$570		Add to Cart
BHA21004647-9	A06901-HRP	HRP	100 ug	$570		Add to Cart
BHA21004647-10	A06901-APC	APC	100 ug	$670		Add to Cart
BHA21004647-11	A06901-PE	PE	100 ug	$670		Add to Cart
BHA21004647-12	A06901-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004647-13	A06901-carrier-free	carrier-free	100 ug	$370		Add to Cart

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