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Home / Primary Antibodies / Polyclonal Antibodies

Anti-TRAP1 Antibody Picoband®

SKU : BHA21000741

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Mfr.No.	PB9834, PB9834-10ug, PB9834-Biotin, PB9834-Cy3, PB9834-Dylight488, PB9834-Dylight550, PB9834-Dylight594, PB9834-FITC, PB9834-HRP, PB9834-APC, PB9834-PE, PB9834-iFluor647, PB9834-carrier-free
Alternative Names	Heat shock protein 75 kDa, mitochondrial
Background	Heat shock protein 75 kDa, mitochondrial is a protein that in humans is encoded by the TRAP1 gene. It is mapped to 16p13.3. This gene encodes a mitochondrial chaperone protein that is member of the heat shock protein 90 (HSP90) family. The encoded protein has ATPase activity and interacts with tumor necrosis factor type I. And this protein may function in regulating cellular stress responses. In addition, it was found that TRAP1 interacted with the N-terminal half of TNFR1. Also, TRAP1 interacted with the C-terminal ends of the proteins encoded by both multiple exostoses-causing genes, EXT1 and EXT2, but not with EXTL1 or EXTL3.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-TRAP1 Antibody Picoband® catalog # PB9834. Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance b
Host	Rabbit
Immunogen Region	E.coli-derived human TRAP1 recombinant protein (Position: A571-H704). Human TRAP1 shares 91.7% and 94% amino acid (aa) sequence identity with mouse and rat TRAP1, respectively.
Isotype	Rabbit IgG
Molecular Weight	80 kDa
Reactivity	Human, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Heat shock protein 75 kDa, mitochondrial;HSP 75;TNFR-associated protein 1;Tumor necrosis factor type 1 receptor-associated protein;TRAP-1;TRAP1;HSP75;
Tissue Specificity	Found in skeletal muscle, liver, heart, brain, kidney, pancreas, lung, placenta and bladder. Expression is higly reduced in bladder cancer and renal cell carcinoma specimens compared to healthy tissues, but it is increased in other type of tumors. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q12931
Gene Id	10131
Gene Name	TRAP1
Subcellular Location	Mitochondrion . Mitochondrion inner membrane . Mitochondrion matrix .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat Western blot, 0.1-0.5ug/ml, Human, Rat

Reference	1. "Entrez Gene: TRAP1 TNF receptor-associated protein 1". 2. Felts SJ, Owen BA, Nguyen P, Trepel J, Donner DB, Toft DO (March 2000). "The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties". J Biol Chem 275 (5): 330512. 3. Song HY, Dunbar JD, Zhang YX, Guo D, Donner DB (March 1995). "Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor". J Biol Chem 270 (8): 357481.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000741-1	PB9834	100 ug	-	$370		Add to Cart
BHA21000741-2	PB9834-10ug	10 ug	Sample	$99		Add to Cart
BHA21000741-3	PB9834-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000741-4	PB9834-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000741-5	PB9834-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000741-6	PB9834-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000741-7	PB9834-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000741-8	PB9834-FITC	100 ug	FITC	$570		Add to Cart
BHA21000741-9	PB9834-HRP	100 ug	HRP	$570		Add to Cart
BHA21000741-10	PB9834-APC	100 ug	APC	$670		Add to Cart
BHA21000741-11	PB9834-PE	100 ug	PE	$670		Add to Cart
BHA21000741-12	PB9834-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000741-13	PB9834-carrier-free	100 ug	carrier-free	$370		Add to Cart

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