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Home / Primary Antibodies / Polyclonal Antibodies

Anti-TNFRSF14 Antibody

SKU : BHA21002161

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Mfr.No.	A02298, A02298-10ug, A02298-Biotin, A02298-Cy3, A02298-Dylight488, A02298-Dylight550, A02298-Dylight594, A02298-FITC, A02298-HRP, A02298-APC, A02298-PE, A02298-iFluor647, A02298-carrier-free
Alternative Names	Tumor necrosis factor receptor superfamily member 14
Background	Herpesvirus entry mediator (HVEM), also known as tumor necrosis factor receptor superfamily member 14 (TNFRSF14), is a human cell surface receptor of the TNF-receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alteative splicing results in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-TNFRSF14 Antibody Picoband® catalog # A02298. Tested in ELISA applications. This antibody reacts with Human.
Function	Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into C
Host	Rabbit
Immunogen Region	E. coli-derived human TNFRSF14/HVEM recombinant protein (Position: L39-V202).
Isotype	Rabbit IgG
Molecular Weight	170 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Tumor necrosis factor receptor superfamily member 14;Herpes virus entry mediator A;Herpesvirus entry mediator A;HveA;Tumor necrosis factor receptor-like 2;TR2;CD270;TNFRSF14;HVEA, HVEM;UNQ329/PRO509;
Tissue Specificity	Widely expressed, with the highest expression in lung, spleen and thymus.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q92956
Gene Id	8764
Gene Name	TNFRSF14
Subcellular Location	Membrane ; Single-pass type I membrane protein .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA
Description	ELISA Capture (Matched Antibody Pair), 2-8ug/ml<br>

Reference	1. Kwon BS, Tan KB, Ni J, Oh KO, Lee ZH, Kim KK, Kim YJ, Wang S, Gentz R, Yu GL, Harrop J, Lyn SD, Silverman C, Porter TG, Truneh A, Young PR (June 1997). "A newly identified member of the tumor necrosis factor receptor superfamily with a wide tissue distribution and involvement in lymphocyte activation". J Biol Chem 272 (22): 142726.<br /><br />2. Montgomery RI, Waer MS, Lum BJ, Spear PG (Dec 1996). "Herpes simplex virus-1 entry into cells mediated by a novel member of the TNF/NGF receptor family". Cell 87 (3): 42736. <br /><br />3. Ware, Carl (2008). "Chapter 25: TNF-Related Cytokines in Immunity". In Paul, William. Fundamental Immunology (Book) (6th ed.). Philadelphia: Lippincott Williams & Wilkins. pp. 776801.<br /><br />4. Schmidt-Ott KM, Mori K, Li JY, Kalandadze A, Cohen DJ, Devarajan P, Barasch J (February 2007). "Dual action of neutrophil gelatinase-associated lipocalin". J. Am. Soc. Nephrol. 18 (2): 40713.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002161-1	A02298	-	100 ug	$370		Add to Cart
BHA21002161-2	A02298-10ug	Sample	10 ug	$99		Add to Cart
BHA21002161-3	A02298-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002161-4	A02298-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002161-5	A02298-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002161-6	A02298-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002161-7	A02298-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002161-8	A02298-FITC	FITC	100 ug	$570		Add to Cart
BHA21002161-9	A02298-HRP	HRP	100 ug	$570		Add to Cart
BHA21002161-10	A02298-APC	APC	100 ug	$670		Add to Cart
BHA21002161-11	A02298-PE	PE	100 ug	$670		Add to Cart
BHA21002161-12	A02298-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002161-13	A02298-carrier-free	carrier-free	100 ug	$370		Add to Cart

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