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Home / Primary Antibodies / Polyclonal Antibodies

Anti-TNF Receptor I/TNFRSF1A Antibody Picoband®

SKU : BHA21003899

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Mfr.No.	A00294-4, A00294-4-10ug, A00294-4-Biotin, A00294-4-Cy3, A00294-4-Dylight488, A00294-4-Dylight550, A00294-4-Dylight594, A00294-4-FITC, A00294-4-HRP, A00294-4-APC, A00294-4-PE, A00294-4-iFluor647, A00294-4-carrier-free
Alternative Names	TNF receptor superfamily member 1A
Background	Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A), also known as TNFR1, is a protein that in humans is encoded by the TNFRSF1A gene. The protein encoded by this gene is a member of the Tumor necrosis factor receptor superfamily, which also contains TNFRSF1B. The TNFR1 gene is mapped to 12pter-cen. It encodes a protein of 455 amino acids. And this receptor can activate the transcription factor NF-kappaB, mediate apoptosis, and function as a regulator of inflammation.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-TNF Receptor I/TNFRSF1A Antibody Picoband® catalog # A00294-4. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiate
Host	Rabbit
Immunogen Region	E.coli-derived human TNF Receptor I/TNFRSF1A recombinant protein (Position: N336-A440).
Isotype	Rabbit IgG
Molecular Weight	60-70 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60; CD120a; Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1; TBPI; TNFRSF1A; TNFAR; TNFR1
Tissue Specificity	Activated T-cells. Highly expressed on tonsillar T-cells, which are closely associated with B-cells in the apical light zone of germinal centers, the site of terminal B- cell maturation. Expressed at lower levels in thymus, lung, lymph node and peripheral blood leukocytes. Expressed in the medulla of fetal and newbo thymus.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P19438
Gene Id	7132
Gene Name	TNFRSF1A
Subcellular Location	Cell membrane.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	ELISA, Flow Cytometry, WB
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Baker E, Chen LZ, Smith CA, Callen DF, Goodwin R, Sutherland GR (Nov 1991). "Chromosomal location of the human tumor necrosis factor receptor genes". Cytogenet Cell Genet 57 (2-3): 1178. 2. Schall TJ, Lewis M, Koller KJ, Lee A, Rice GC, Wong GH, Gatanaga T, Granger GA, Lentz R, Raab H, et al. (Jun 1990). "Molecular cloning and expression of a receptor for human tumor necrosis factor". Cell 61 (2): 36170.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003899-1	A00294-4	-	100 ug	$370		Add to Cart
BHA21003899-2	A00294-4-10ug	Sample	10 ug	$99		Add to Cart
BHA21003899-3	A00294-4-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003899-4	A00294-4-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003899-5	A00294-4-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003899-6	A00294-4-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003899-7	A00294-4-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003899-8	A00294-4-FITC	FITC	100 ug	$570		Add to Cart
BHA21003899-9	A00294-4-HRP	HRP	100 ug	$570		Add to Cart
BHA21003899-10	A00294-4-APC	APC	100 ug	$670		Add to Cart
BHA21003899-11	A00294-4-PE	PE	100 ug	$670		Add to Cart
BHA21003899-12	A00294-4-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003899-13	A00294-4-carrier-free	carrier-free	100 ug	$370		Add to Cart

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