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Home / Primary Antibodies / Polyclonal Antibodies

Anti-TMEM107 Antibody Picoband®

SKU : BHA21001199

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Mfr.No.	A04966, A04966-10ug, A04966-Biotin, A04966-Cy3, A04966-Dylight488, A04966-Dylight550, A04966-Dylight594, A04966-FITC, A04966-HRP, A04966-APC, A04966-PE, A04966-iFluor647, A04966-carrier-free
Alternative Names	Transmembrane protein 107
Background	Cilia are dynamic signaling organelles essential for developmental patteing, including left-right specification, skeletal formation, neural development, and organogenesis. TMEM107 is predicted to be critical for cilia formation and signaling in a subset of embryonic tissues. Based on an alignment of theTMEM107 sequence with the genomic sequence (GRCh38), the TMEM107 gene was mapped to chromosome 17p13.1.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-TMEM107 Antibody Picoband® catalog # A04966. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Plays a role in cilia formation and embryonic patteing. Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GLI3 to patte ventral and intermediate neuronal cell types (By similarity). .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human TMEM107, different from the related mouse and rat sequences by four amino acids.
Isotype	Rabbit IgG
Molecular Weight	22 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Transmembrane protein 107;TMEM107;DC20, UNQ638/PRO1268;
Tissue Specificity	Ubiquitous. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q6UX40
Gene Id	84314
Gene Name	TMEM107
Subcellular Location	Membrane ; Multi-pass membrane protein .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Christopher, K. J., Wang, B., Kong, Y., Weatherbee, S. D. Forward genetics uncovers transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signaling. Dev. Biol. 368: 382-392, 2012.<br /><br />2. Hartz, P. A. Personal Communication. Baltimore, Md. 1/12/2015.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001199-1	A04966	100 ug	-	$370		Add to Cart
BHA21001199-2	A04966-10ug	10 ug	Sample	$99		Add to Cart
BHA21001199-3	A04966-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001199-4	A04966-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001199-5	A04966-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001199-6	A04966-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001199-7	A04966-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001199-8	A04966-FITC	100 ug	FITC	$570		Add to Cart
BHA21001199-9	A04966-HRP	100 ug	HRP	$570		Add to Cart
BHA21001199-10	A04966-APC	100 ug	APC	$670		Add to Cart
BHA21001199-11	A04966-PE	100 ug	PE	$670		Add to Cart
BHA21001199-12	A04966-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001199-13	A04966-carrier-free	100 ug	carrier-free	$370		Add to Cart

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