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Home / Primary Antibodies / Polyclonal Antibodies

Anti-TIMP1 Antibody Picoband®

SKU : BHA21001375

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Mfr.No.	A00561, A00561-10ug, A00561-Biotin, A00561-Cy3, A00561-Dylight488, A00561-Dylight550, A00561-Dylight594, A00561-FITC, A00561-HRP, A00561-APC, A00561-PE, A00561-iFluor647, A00561-carrier-free
Alternative Names	TIMP metallopeptidase inhibitor 1
Background	TIMP metallopeptidase inhibitor 1, also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. This protein is a member of the TIMP family. The glycoprotein is a natural inhibitor of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. TIMP was found to be located about 22 cM proximal to OTC (300461).
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-TIMP1 Antibody Picoband® catalog # A00561. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP
Host	Rabbit
Immunogen Region	E. coli-derived human TIMP1 recombinant protein (Position: C24-A207).
Isotype	Rabbit IgG
Molecular Weight	23 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Metalloproteinase inhibitor 1; Erythroid-potentiating activity; EPA; Fibroblast collagenase inhibitor; Collagenase inhibitor; Tissue inhibitor of metalloproteinases 1; TIMP-1; TIMP1; CLGI, TIMP;
Tissue Specificity	Detected in rheumatoid synovial fluid (at protein level).
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	TIMP1: P01033
Gene Id	7076
Gene Name	TIMP1
Subcellular Location	Secreted

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, WB
Description	Weste blot, 0.1-0.5ug/ml<br> ELISA, 0.1-0.5ug/ml<br>

Reference	1. Anderson, C. L., Brown, C. J. Polymorphic X-chromosome inactivation of the human TIMP1 gene. Am. J. Hum. Genet. 65: 699-708, 1999.<br /><br />2. Zeiss, C. J., Acland, G. M., Aguirre, G. D., Ray, K. TIMP-1 expression is increased in X-linked progressive retinal atrophy despite its exclusion as a candidate gene. Gene 225: 67-75, 1998.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001375-1	A00561	100 ug	-	$370		Add to Cart
BHA21001375-2	A00561-10ug	10 ug	Sample	$99		Add to Cart
BHA21001375-3	A00561-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001375-4	A00561-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001375-5	A00561-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001375-6	A00561-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001375-7	A00561-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001375-8	A00561-FITC	100 ug	FITC	$570		Add to Cart
BHA21001375-9	A00561-HRP	100 ug	HRP	$570		Add to Cart
BHA21001375-10	A00561-APC	100 ug	APC	$670		Add to Cart
BHA21001375-11	A00561-PE	100 ug	PE	$670		Add to Cart
BHA21001375-12	A00561-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001375-13	A00561-carrier-free	100 ug	carrier-free	$370		Add to Cart

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