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Home / Primary Antibodies / Polyclonal Antibodies

Anti-TEF1/TEAD-1/TEAD1 Antibody Picoband®

SKU : BHA21003311

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Mfr.No.	A03263-2, A03263-2-10ug, A03263-2-Biotin, A03263-2-Cy3, A03263-2-Dylight488, A03263-2-Dylight550, A03263-2-Dylight594, A03263-2-FITC, A03263-2-HRP, A03263-2-APC, A03263-2-PE, A03263-2-iFluor647, A03263-2-carrier-free
Alternative Names	pyruvate dehydrogenase kinase, isozyme 2
Background	Transcriptional enhancer factor TEF-1 also known as TEA domain family member 1 (TEAD1) and transcription factor 13 (TCF-13) is a protein that in humans is encoded by the TEAD1 gene. This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein s the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have been described but their full-length natures have not been experimentally verified.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-TEF1/TEAD-1/TEAD1 Antibody Picoband® catalog # A03263-2. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Kinase that plays a key role in the regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite
Host	Rabbit
Immunogen Region	E.coli-derived human TEF1/TEAD-1/TEAD1 recombinant protein (Position: D38-D426).
Isotype	Rabbit IgG
Molecular Weight	50 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	(Pyruvate dehydrogenase (acetyl-transferring)) kinase isozyme 2; mitochondrial; Pyruvate dehydrogenase kinase isoform 2; PDH kinase 2; PDKII; PDK2; PDHK2
Tissue Specificity	Expressed in many tissues, with the highest level in heart and skeletal muscle, intermediate levels in brain, kidney, pancreas and liver, and low levels in placenta and lung.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4.

Uniprot	P28347
Gene Id	7003
Gene Name	TEAD1
Subcellular Location	Mitochondrion matrix.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, WB
Description	Weste blot, 0.25-0.5ug/ml, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Blatt, C., DePamphilis, M. L. Striking homology between mouse and human transcription enhancer factor-1 (TEF-1). Nucleic Acids Res. 21: 747-748, 1993. <br /><br />2. Chen, Z., Friedrich, G. A., Soriano, P. Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice. Genes Dev. 8: 2293-2301, 1994.<br /><br />3. Fossdal, R., Jonasson, F., Kristjansdottir, G. T., Kong, A., Stefansson, H., Gosh, S., Gulcher, J. R., Stefansson, K. A novel TEAD1 mutation is the causative allele in Sveinsson's chorioretinal atrophy (helicoid peripapillary chorioretinal degeneration). Hum. Molec. Genet. 13: 975-981, 2004. <br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003311-1	A03263-2	-	100 ug	$370		Add to Cart
BHA21003311-2	A03263-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21003311-3	A03263-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003311-4	A03263-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003311-5	A03263-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003311-6	A03263-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003311-7	A03263-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003311-8	A03263-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21003311-9	A03263-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21003311-10	A03263-2-APC	APC	100 ug	$670		Add to Cart
BHA21003311-11	A03263-2-PE	PE	100 ug	$670		Add to Cart
BHA21003311-12	A03263-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003311-13	A03263-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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