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Home / Primary Antibodies / Polyclonal Antibodies

Anti-TATA binding protein TBP Antibody Picoband®

SKU : BHA21006869

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Mfr.No.	PA1534, PA1534-10ug, PA1534-Biotin, PA1534-Cy3, PA1534-Dylight488, PA1534-Dylight550, PA1534-Dylight594, PA1534-FITC, PA1534-HRP, PA1534-APC, PA1534-PE, PA1534-iFluor647, PA1534-carrier-free
Alternative Names	TATA-box-binding protein
Background	TBP, TATA-binding protein, is a general transcription factor that binds specifically to a DNA sequence called the TATA box. The TBP gene is mapped to 6q27. This DNA sequence is found about 35 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in tu makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitiation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20% of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-TATA binding protein TBP Antibody catalog # PA1534. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre- initiation complex (PIC), playing a role in the activation of eukaryotic
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human TBP, identical to the related rat and mouse sequences.
Isotype	Rabbit IgG
Molecular Weight	31 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	TATA-box-binding protein;TATA sequence-binding protein;TATA-binding factor;TATA-box factor;Transcription initiation factor TFIID TBP subunit;TBP;GTF2D1, TF2D, TFIID;
Tissue Specificity	Widely expressed, with levels highest in the testis and ovary. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P20226
Gene Name	TBP
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat <br>

Reference	1. Bauer, P., Laccone, F., Rolfs, A., Wullner, U., Bosch, S., Peters, H., Liebscher, S., Scheible, M., Epplen, J. T., Weber, B. H. F., Holinski-Feder, E., Weirich-Schwaiger, H., Morris-Rosendahl, D. J., Andrich, J., Riess, O.Trinucleotide repeat expansion in SCA17/TBP in white patients with Huntington's disease-like phenotype.J. Med. Genet. 41: 230-232, 2004.<br /><br />2. Stevanin, G., Fujigasaki, H., Lebre, A.-S., Camuzat, A., Jeannequin, C., Dode, C., Takahashi, J., San, C., Bellance, R., Brice, A., Durr, A.Huntington's disease-like phenotype due to trinucleotide repeat expansions in the TBP and JPH3 genes.Brain 126: 1599-1603, 2003.<br /><br />3. Veenstra, G. J. C., Weeks, D. L., Wolffe, A. P.Distinct roles for TBP and TBP-like factor in early embryonic gene transcription in Xenopus.Science 290: 2312-2314, 2000.<br /><br /><br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006869-1	PA1534	-	100 ug	$370		Add to Cart
BHA21006869-2	PA1534-10ug	Sample	10 ug	$99		Add to Cart
BHA21006869-3	PA1534-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006869-4	PA1534-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006869-5	PA1534-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006869-6	PA1534-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006869-7	PA1534-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006869-8	PA1534-FITC	FITC	100 ug	$570		Add to Cart
BHA21006869-9	PA1534-HRP	HRP	100 ug	$570		Add to Cart
BHA21006869-10	PA1534-APC	APC	100 ug	$670		Add to Cart
BHA21006869-11	PA1534-PE	PE	100 ug	$670		Add to Cart
BHA21006869-12	PA1534-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006869-13	PA1534-carrier-free	carrier-free	100 ug	$370		Add to Cart

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