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Home / Primary Antibodies / Polyclonal Antibodies

Anti-TAP2 Antibody Picoband®

SKU : BHA21000724

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Mfr.No.	PB9824, PB9824-10ug, PB9824-Biotin, PB9824-Cy3, PB9824-Dylight488, PB9824-Dylight550, PB9824-Dylight594, PB9824-FITC, PB9824-HRP, PB9824-APC, PB9824-PE, PB9824-iFluor647, PB9824-carrier-free
Alternative Names	Antigen peptide transporter 2
Background	Transporter, ATP-binding cassette, major histocompatibility complex 2 (TAP2) is a gene in humans that encodes the protein Antigen peptide transporter 2. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. The gene is assigned to human chromosome 6p21.3. It is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. And this protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-TAP2 Antibody Picoband® catalog # PB9824. Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC clas
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human TAP2, different from the related mouse sequence by five amino acids, and from the related rat sequence by six amino acids.
Isotype	Rabbit IgG
Molecular Weight	87 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Antigen peptide transporter 2;APT2;ATP-binding cassette sub-family B member 3;Peptide supply factor 2;Peptide transporter PSF2;PSF-2;Peptide transporter TAP2;Peptide transporter involved in antigen processing 2;Really interesting new gene 11 protein;TAP2;ABCB3, PSF2, RING11, Y1;
Tissue Specificity	Expressed highly in placenta, prostate and trachea and lower expression in the small intestine and lung. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q03519
Gene Id	6891
Gene Name	TAP2
Subcellular Location	Endoplasmic reticulum membrane; Multi-pass membrane protein. The transmembrane segments seem to form a pore in the membrane.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human

Reference	1. Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Dupont B, Erlich HA, Mach B, Mayr WR, Parham P (Oct 1992). "Nomenclature for factors of the HLA system, 1991. WHO Nomenclature Committee for factors of the HLA system". Tissue Antigens 39 (4): 16173. 2. Bahram S, Aold D, Bresnahan M, Strominger JL, Spies T (Dec 1991). "Two putative subunits of a peptide pump encoded in the human major histocompatibility complex class II region". Proc Natl Acad Sci U S A 88 (22): 100948. 3. Hahn Y, Lee B (Feb 2006). "Human-specific nonsense mutations identified by genome sequence comparisons". Hum Genet 119 (12): 16978.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000724-1	PB9824	100 ug	-	$370		Add to Cart
BHA21000724-2	PB9824-10ug	10 ug	Sample	$99		Add to Cart
BHA21000724-3	PB9824-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000724-4	PB9824-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000724-5	PB9824-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000724-6	PB9824-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000724-7	PB9824-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000724-8	PB9824-FITC	100 ug	FITC	$570		Add to Cart
BHA21000724-9	PB9824-HRP	100 ug	HRP	$570		Add to Cart
BHA21000724-10	PB9824-APC	100 ug	APC	$670		Add to Cart
BHA21000724-11	PB9824-PE	100 ug	PE	$670		Add to Cart
BHA21000724-12	PB9824-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000724-13	PB9824-carrier-free	100 ug	carrier-free	$370		Add to Cart

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