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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Talin 1/TLN1 Antibody Picoband®

SKU : BHA21002875

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Mfr.No.	A02859-2, A02859-2-10ug, A02859-2-Biotin, A02859-2-Cy3, A02859-2-Dylight488, A02859-2-Dylight550, A02859-2-Dylight594, A02859-2-FITC, A02859-2-HRP, A02859-2-APC, A02859-2-PE, A02859-2-iFluor647, A02859-2-carrier-free
Alternative Names	talin 1
Background	Talin-1 is a protein that in humans is encoded by the TLN1 gene. This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Talin 1/TLN1 Antibody Picoband® catalog # A02859-2. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts (By similarity).
Host	Rabbit
Immunogen Region	E.coli-derived human Talin 1/TLN1 recombinant protein (Position: Q1658-N1876).
Isotype	Rabbit IgG
Molecular Weight	270 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Talin-1; TLN1; KIAA1027; TLN
Tissue Specificity	Placenta and skin. Predominantly expressed in mammary gland tissue.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	Q9Y490
Gene Id	7094
Gene Name	TLN1
Subcellular Location	Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. Cell surface.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, IF, IHC, ICC, WB, Flow Cytometry
Description	Weste blot, 0.1-0.25ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br> Flow Cytometry(Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Rees, D. J. G.; Ades, S. E.; Singer, S. J.; Hynes, R. O. : Sequence and domain structure of talin. Nature 347: 685-689, 1990. <br /><br />2. Gilmore, A. P.; Ohanian, V.; Spurr, N. K.; Critchley, D. R. : Localisation of the human gene encoding the cytoskeletal protein talin to chromosome 9p. Hum. Genet. 96: 221-224, 1995.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002875-1	A02859-2	-	100 ug	$370		Add to Cart
BHA21002875-2	A02859-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21002875-3	A02859-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002875-4	A02859-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002875-5	A02859-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002875-6	A02859-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002875-7	A02859-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002875-8	A02859-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21002875-9	A02859-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21002875-10	A02859-2-APC	APC	100 ug	$670		Add to Cart
BHA21002875-11	A02859-2-PE	PE	100 ug	$670		Add to Cart
BHA21002875-12	A02859-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002875-13	A02859-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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