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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Synapsin I/SYN1 Antibody Picoband®

SKU : BHA21001004

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Mfr.No.	PB10099, PB10099-10ug, PB10099-Biotin, PB10099-Cy3, PB10099-Dylight488, PB10099-Dylight550, PB10099-Dylight594, PB10099-FITC, PB10099-HRP, PB10099-APC, PB10099-PE, PB10099-iFluor647, PB10099-carrier-free
Alternative Names	Synapsin-1
Background	Synapsin I, is the collective name for Synapsin Ia and Synapsin Ib, two nearly identical phosphoproteins that in humans are encoded by the SYN1 gene. This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alteatively spliced transcript variants encoding different isoforms have been identified.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Synapsin I/SYN1 Antibody Picoband® catalog # PB10099. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human Synapsin I, identical to the related mouse and rat sequences.
Isotype	Rabbit IgG
Molecular Weight	78 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Synapsin-1;Brain protein 4.1;Synapsin I;SYN1;
Tissue Specificity	Ubiquitous. Expressed in leukocytes and plasma. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P17600
Gene Id	6853
Gene Name	SYN1
Subcellular Location	Cell junction, synapse. Golgi apparatus .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat<br>Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br>

Reference	1. "Entrez Gene: SYN1 synapsin I".<br /><br />2. Huttner WB, Schiebler W, Greengard P, De Camilli P (May 1983). "Synapsin I (protein I), a nerve terminal-specific phosphoprotein. III. Its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation". J. Cell Biol. 96 (5): 137488.<br /><br />3. Südhof TC (May 1990). "The structure of the human synapsin I gene and protein". J. Biol. Chem. 265 (14): 784952.<br /><br />

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001004-1	PB10099	100 ug	-	$370		Add to Cart
BHA21001004-2	PB10099-10ug	10 ug	Sample	$99		Add to Cart
BHA21001004-3	PB10099-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001004-4	PB10099-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001004-5	PB10099-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001004-6	PB10099-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001004-7	PB10099-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001004-8	PB10099-FITC	100 ug	FITC	$570		Add to Cart
BHA21001004-9	PB10099-HRP	100 ug	HRP	$570		Add to Cart
BHA21001004-10	PB10099-APC	100 ug	APC	$670		Add to Cart
BHA21001004-11	PB10099-PE	100 ug	PE	$670		Add to Cart
BHA21001004-12	PB10099-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001004-13	PB10099-carrier-free	100 ug	carrier-free	$370		Add to Cart

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